5'6'7'8-TETRAHYDROFOLATE
THF
F5THF+Glu=FGlu+THF
FIMTHF+Glu=FIGlu+THF
FIGLU+THF=FIMTHF+GLU
LPEAM+THF=CH2THF+LPEDH+NH3
LPEAM+THF=CH2THF+NH3+LPEDH
DHF+NADH=THF+NAD
DHF+NADPH=THF+NADP
ATP+FORM+THF=ADP+Pi+F10THF
THF+SER=CH2THF+GLY+H2O
F10THF+GAR=FGAR+THF
CH2THF+AKIW=THF+DHPAN
F10THF+H2O=FORM+THF
F10THF+AICAR=THF+FAICAR
SER+THF=CH2THF+GLY+H2O
GLY+THF+NAD=CH2THF+CO2+NH3+NADH
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