Рис. F 3 seq
Нуклеотидная и аминокислотная последовательности
гена фактора коагуляции 3 человека
aagac
tgcgagctccccgcaccccctcgcactccctctggccggcccagggcgccttcagccca
acctccccagccccacgggcgccacggaacccgctcgatctcgccgccaactggtagac
-32
atg gag acc cct gcc tgg ccc cgg gtc ccg cgc ccc gag acc gcc
met glu thr pro ala trp pro arg val pro arg pro glu thr ala 15
gtc gct cgg acg ctc ctg ctc ggc tgg gtc ttc gcc cag gtg gcc
val ala arg thr leu leu leu gly trp val phe ala gln val ala 30
ggc gct tca ggc act aca aat act gtg gca gca tat aat tta act
gly ala ser gly thr thr asn thr val ala ala tyr asn leu thr 45
tgg aaa tca act aat ttc aag aca att ttg gag tgg gaa ccc aaa
trp lys ser thr asn phe lys thr ile leu glu trp glu pro lys 60
ccc gtc aat caa gtc tac act gtt caa ata agc act aag tca gga
pro val asn gln val tyr thr val gln ile ser thr lys ser gly 75
gat tgg aaa agc aaa tgc ttt tac aca aca gac aca gag tgt gac
asp trp lys ser lys cys phe tyr thr thr asp thr glu cys asp 90
ctc acc gac gag att gtg aag gat gtg aag cag acg tac ttg gca
leu thr asp gly ile val lys asp val lys gln thr tyr leu ala 105
cgg gtc ttc tcc tac ccg gca ggg aat gtg gag agc acc ggt tct
arg val phe ser tyr pro ala gly asn val glu ser thr gly ser 120
gct ggg gag cct ctg tat gag aac tcc cca gag ttc aca cct tac
ala gly glu pro leu tyr glu asn ser pro glu phe thr pro tyr 135
ctg gag aca aac ctc gga cag cca aca att cag agt ttt gaa cag
leu glu thr asn leu glu gln pro thr ile gln ser phe glu gln 150
gtg gga aca aaa gtg aat gtg acc gta gaa gat gaa cgg act tta
val gly thr lys val asn val thr val glu asp glu arg thr leu 165
gtc aga agg aac aac act ttc cta agc ctc cgg gat gtt ttt ggc
val arg arg asn asn thr phe leu ser leu arg asp val phe gly 180
aag gac tta att tat aca ctt tat tat tgg aaa tct tca agt tca
lys asp leu ile tyr thr leu tyr tyr trp lys ser ser ser ser 195
gga aag aaa aca gcc aaa aca aac act aat gag ttt ttg att gat
gly lys lys thr ala lys thr asn thr asn glu phe leu ile asp 210
gtg gat aaa gga gaa aac tac tgt ttc agt gtt caa gca gtg att
val asp lys gly glu asn tyr cys phe ser val gln ala val ile 225
ccc tcc cga aca gtt aac cgg aag agt aca gac agc ccg gta gag
pro ser arg thr val asn arg lys ser thr asp ser pro val glu 240
tgt atg ggc cag gag aaa ggg gaa ttc aga gaa ata ttc tac atc
cys met gly gln glu lys gly glu phe arg glu ile phe tyr ile 255
att gga gct gtg gta ttt gtg gtc atc atc ctt gtc atc atc ctg
ile gly ala val val phe val val ile ile leu val ile ile leu 270
gct ata tct cta cac aag tgt aga aag gca gga gtg ggg cag agc
ala ile ser leu his lys cys arg lys ala gly val gly gln ser 285
tgg aag gag aac tcc cca ctg aat gtt tca taa aggaagcactgttgg
trp lys glu asn ser pro leu asn val ser ter
agc tac tgc aaa tgc tat att gca ctg tga ccg aga act tttaaga
ggatagaatacatggaaacgcaaatgagtatttcggagcatgaagaccctggagttcaa
aaaactcttgatatgacctgttattaccattagcattctggttttgacatcagcattagt
cactttgaaatgtaacgaatggtactacaaccaattccaagttttaatttttaacaccat
ggcaccttttgcacataacatgctttagattatatattccgcacttaaggattaaccagg
tcgtccaagcaaaaacaaatgggaaaatgtcttaaaaaatcctgggtggacttttgaaaa
gcttttttttttttttttttttgagacggagtcttgctctgttgcccaggctggagtgca
gtagcacgatctcggctcacttgcaccctccgtctctcgggttcaagcaattgtctgcct
cagcctcccgagtagctgggattacaggtgcgcactaccacgccaagctaatttttgtat
tttttagtagagatggggtttcaccatcttggccaggctggtcttgaattcctgacctca
gtgatccacccaccttggcctcccaaagatgctagtattatgggcgtgaaccaccatgcc
cagccgaaaagcttttgaggggctgacttcaatccatgtaggaaagtaaaatggaaggaa
attgggtgcatttctaggacttttctaacatatgtctataatatagtgtttaggttcttt
tttttttcaggaatacatttggaaattcaaaacaattgggcaaactttgtattaatgtgt
taagtgcaggagacattggtattctgggcagcttcctaatatgctttacaatctgcactt
taactgacttaagtggcattaaacatttgagagctaactatatttttataagactactat
acaaactacagagtttatgatttaaggtacttaaagcttctatggttgacattgtatata
taattttttaaaaaggtttttctatatggggattttctatttatgtaggtaatattgttc
tatttgtatatattgagataatttatttaatatactttaaataaaggtgactgggaattg
tt
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