Рис. KH seq.


         Нуклеотидная и аминокислотная последовательности
               гена фруктокиназы (кетогексокиназы)
                (fructokinase; ketohexokinase)
                          (KH) человека.


ATG GAA GAG AAG CAG ATC CTG TGC GTG GGG CTA GTG GTG CTG GAC
met glu glu lys gln ile leu cys val gly leu val val leu asp  15

GTC ATC AGC CTG GTG GAC AAG TAC CCT AAG GAG GAC TCG GAG ATA
val ile ser leu val asp lys tyr pro lys glu asp ser glu ile  30

AGG TGT TTG TCC CAG AGA TGG CAG CGC GGA GGC AAC GCG TCC AAC
arg cys leu ser gln arg trp gln arg gly gly asn ala ser asn  45

TCC TGC ACC GTT CTC TCC CTG CTC GGA GCC CCC TGT GCC TTC ATG
ser cys thr val leu ser leu leu gly ala pro cys ala phe met  60

GGC TCA ATG GCT CCT GGC CAT GTT GCT GAT TTT GTC CTG GAT GAC
gly ser met ala pro gly his val ala asp phe val leu asp asp  75

CTC CGC CGC TAT TCT GTG GAC CTA CGC TAC ACA GTC TTT CAG ACC
leu arg arg tyr ser val asp leu arg tyr thr val phe gln thr  90

ACA GGC TCC GTC CCC ATC GCC ACG GTC ATC ATC AAC GAG GCC AGT
thr gly ser val pro ile ala thr val ile ile asn glu ala ser 105

GGT AGC CGC ACC ATC CTA TAC TAT GAC AGG AGC CTG CCA GAT GTG
gly ser arg thr ile leu tyr tyr asp arg ser leu pro asp val 120

TCT GCT ACA GAC TTT GAG AAG GTT GAT CTG ACC CAG TTC AAG TGG
ser ala thr asp phe glu lys val asp leu thr gln phe lys trp 135

ATC CAC ATT GAG GGC CGG AAC GCA TCG GAG CAG GTG AAG ATG CTG
ile his ile glu gly arg asn ala ser glu gln val lys met leu 150

CAG CGG ATA GAC GCA CAC AAC ACC AGG CAG CCT CCA GAG CAG AAG
gln arg ile asp ala his asn thr arg gln pro pro glu gln lys 165

ATC CGG GTG TCC GTG GAG GTG GAG AAG CCA CGA GAG GAG CTC TTC
ile arg val ser val glu val glu lys pro arg glu glu leu phe 180

CAG CTG TTT GGC TAC GGA GAC GTG GTG TTT GTC AGC AAA GAT GTG
gln leu phe gly tyr gly asp val val phe val ser lys asp val 195

GCC AAG CAC TTG GGG TTC CAG TCA GCA GAG GAA GCC TTG AGG GGC
ala lys his leu gly phe gln ser ala glu glu ala leu arg gly 210

TTG TAT GGT CGT GTG AGG AAA GGG GCT GTG CTT GTC TGT GCC TGG
leu tyr gly arg val arg lys gly ala val leu val cys ala trp 225

GCT GAG GAG GGC GCC GAC GCC CTG GGC CCT GAT GGC AAA TTG CTC
ala glu glu gly ala asp ala leu gly pro asp gly lys leu leu 240

CAC TCG GAT GCT TTC CCG CCA CCC CGC GTG GTG GAT ACA CTG GGA
his ser asp ala phe pro pro pro arg val val asp thr leu gly 255

GCT GGA GAC ACC TTC AAT GCC TCC GTC ATC TTC AGC CTC TCC CAG
ala gly asp thr phe asn ala ser val ile phe ser leu ser gln 270

GGG AGG AGC GTG CAG GAA GCA CTG AGA TTC GGG TGC CAG GTG GCC
gly arg ser val gln glu ala leu arg phe gly cys gln val ala 285

GGC AAG AAG TGT GGC CTG CAG GGC TTT GAT GGC ATC GTG TGA
gly lys lys cys gly leu gln gly phe asp gly ile val ter

Смотрите также:

  • Фруктозурия. Строение гена фруктокиназы (KHK)