Рис. Col IV AIV seq
Нуклеотидная и аминокислотная последовательности
гена коллагена IV типа альфа IV (COL IV AIV) человека
ATG TGG TCT CTG CAC ATA GTA CTA ATG AGG TGC TCC TTC AGA TTG
met trp ser leu his ile val leu met arg cys ser phe arg leu 15
ACC AAG TCC TTG GCC ACA GGT CCC TGG TCA CTT ATA CTC ATT CTC
thr lys ser leu ala thr gly pro trp ser leu ile leu ile leu 30
TTT TCT GTA CAA TAT GTA TAT GGG AGT GGA AAG AAA TAC ATT GGT
phe ser val gln tyr val tyr gly ser gly lys lys tyr ile gly 45
CCT TGT GGA GGA AGA GAT TGC TCT GTT TGC CAC TGT GTT CCT GAA
pro cys gly gly arg asp cys ser val cys his cys val pro glu 60
AAG GGG TCT CGG GGT CCA CCA GGA CCA CCA GGG CCA CAG GGT CCA
lys gly ser arg gly pro pro gly pro pro gly pro gln gly pro 75
ATT GGA CCC CTG GGA GCC CCA GGA CCC ATT GGG CTT TCA GGA GAG
ile gly pro leu gly ala pro gly pro ile gly leu ser gly glu 90
AAA GGA ATG AGA GGG GAC CGC GGC CCT CCT GGA GCA GCA GGG GAC
lys gly met arg gly asp arg gly pro pro gly ala ala gly asp 105
AAA GGA GAT AAG GGT CCA ACT GGT GTT CCT GGA TTT CCA GGT TTA
lys gly asp lys gly pro thr gly val pro gly phe pro gly leu 120
GAT GGC ATA CCT GGG CAC CCA GGG CCT CCT GGA CCC AGA GGC AAA
asp gly ile pro gly his pro gly pro pro gly pro arg gly lys 135
CCT GGT ATG AGT GGC CAC AAT GGC TCA AGA GGT GAC CCA GGG TTT
pro gly ,et ser gly his asn gly ser arg gly asp pro gly phe 150
CCA GGA GGA AGA GGA GCT CTT GGC CCA GGA GGC CCC CTA GGC CAT
pro gly gly arg gly ala leu gly pro gly gly pro leu gly his 165
CCT GGG GAA AAG GGA GAA AAA GGA AAT TCA GTG TTC ATT TTA GGT
pro gly glu lys gly glu lys gly asn ser val phe ile leu gly 180
GCC GTT AAA GGT ATT CAG GGA GAC AGA GGG GAC CCA GGA CTG CCT
ala val lys gly ile gln gly asp arg gly asp pro gly leu pro 195
GGC TTA CCA GGA TCT TGG GGT GCA GGA GGA CCG GCA GGT CCC ACA
gly leu pro gly ser trp gly ala gly gly pro ala gly pro thr 210
GGA TAT CCT GGA GAG CCA GGG TTA GTG GGA CCT CCG GGC CAA CCA
gly tyr pro gly glu pro gly leu val gly pro pro gly gln pro 225
GGG CGT CCA GGT TTG AAG GGA AAT CCC GGT GTG GGA GTA AAG GGG
gly arg pro gly leu lys gly asn pro gly val gly val lys gly 240
CAA ATG GGA GAC CCG GGT GAG GTT GGT CAG CAA GGT TCT CCT GGA
gln met gly asp pro gly glu val gly gln gln gly ser pro gly 255
CCC ACC CTG TTG GTA GAG CCA CCT GAC TTT TGT CTC TAT AAA GGA
pro thr leu leu val glu pro pro asp phe cys leu tyr lys gly 270
GAA AAG GGT ATA AAA GGA ATT CCT GGA ATG GTT GGA CTG CCA GGA
glu lys gly ile lys gly ile pro gly met val gly leu pro gly 285
CCA CCA GGA CGC AAG GGA GAA TCT GGT ATT GGG GCA AAA GGA GAA
pro pro gly arg lys gly glu ser gly ile gly ala lys gly glu 300
AAA GGT ATT CCT GGA TTT CCA GGG CCT CGG GGG GAT CCT GGT TCC
lys gly ile pro gly phe pro gly pro arg gly asp pro gly ser 315
TAT GGA TCT CCA GGT TTT CCA GGA TTA AAG GGA GAA CTA GGA CTG
tyr gly ser pro gly phe pro gly leu lys gly glu leu gly leu 330
GTT GGA GAT CCT GGG CTA TTT GGA TTA ATT GGC CCA AAG GGG GAT
val gly asp pro gly leu phe gly leu ile gly pro lys gly asp 345
CCT GGA AAT CGA GGG CAC CCA GGA CCA CCA GGT GTT TTG GTG ACT
pro gly asn arg gly his pro gly pro pro gly val leu val thr 360
CCA CCT CTT CCA CTT AAA GGC CCA CCA GGG GAC CCA GGG TTC CCT
pro pro leu pro leu lys gly pro pro gly asp pro gly phe pro 375
GGC CGC TAT GGA GAA ACA GGG GAT GTT GGA CCA CCT GGT CCC CCA
gly arg tyr gly glu thr gly asp val gly pro pro gly pro pro 390
GGT CTC TTG GGC AGA CCA GGG GAA GCC TGT GCA GGC ATG ATA GGA
gly leu leu gly arg pro gly glu ala cys ala gly met ile gly 405
CCC CCT GGG CCA CAA GGA TTT CCT GGT CTT CCT GGG CTT CCA GGA
pro pro gly pro gln gly phe pro gly leu pro gly leu pro gly 420
GAA GCT GGT ATT CCT GGG AGA CCT GAT TCT GCT CCA GGA AAA CCA
glu ala gly ile pro gly arg pro asp ser ala pro gly lys pro 435
GGG AAG CCA GGA TCA CCT GGC TTG CCT GGA GCA CCA GGC CTG CAG
gly lys pro gly ser pro gly leu pro gly ala pro gly leu gln 450
GGC CTC CCA GGA TCA AGT GTG ATA TAC TGT AGT GTT GGG AAC CCC
gly leu pro gly ser ser val ile tyr cys ser val gly asn pro 465
GGA CCA CAA GGA ATA AAA GGC AAA GTT GGT CCC CCA GGA GGA AGA
gly pro gln gly ile lys gly lys val gly pro pro gly gly arg 480
GGC CCA AAA GGA GAA AAA GGA AAT GAA GGA CTC TGT GCC TGT GAG
gly pro lys gly glu lys gly asn glu gly leu cys ala cys glu 495
CCT GGA CCC ATG GGC CCC CCT GGC CCT CCA GGA CTT CCT GGG AGG
pro gly pro met gly pro pro gly pro pro gly leu pro gly arg 510
CAG GGG AGT AAG GGA GAC TTG GGG CTC CCT GGC TGG CTT GGA ACA
gln gly ser lys gly asp leu gly leu pro gly trp leu gly thr 525
AAA GGT GAC CCA GGA CCT CCT GGT GCT GAA GGA CCT CCA GGG CTA
lys gly asp pro gly pro pro gly ala glu gly pro pro gly leu 540
CCA GGA AAG CAT GGT GCC TCT GGA CCA CCT GGC AAC AAA GGG GCG
pro gly lys his gly ala ser gly pro pro gly asn lys gly ala 555
AAG GGT GAC ATG GTT GTA TCA AGA GTT AAA GGG CAC AAA GGA GAA
lys gly asp met val val ser arg val lys gly his lys gly glu 570
AGA GGT CCT GAT GGG CCC CCA GGA TTT CCA GGG CAG CCA GGA TCA
arg gly pro asp gly pro pro gly phe pro gly gln pro gly ser 585
CAT GGT CGG GAT GGA CAT GCT GGA GAA AAA GGG GAT CCA GGA CCT
his gly arg asp gly his ala gly glu lys gly asp pro gly pro 600
CCA GGG GAT CAT GAA GAT GCG ACC CCA GGT GGT AAA GGA TTT CCT
pro gly asp his glu asp ala thr pro gly gly lys gly phe pro 615
GGA CCT CTG GGC CCC CCA GGC AAA GCA GGA CCT GTT GGG CCC CCA
gly pro leu gly pro pro gly lys ala gly pro val gly pro pro 630
GGA CTG GGA TTT CCT GGT CCA CCA GGA GAG CGA GGC CAC CCA GGA
gly leu gly phe pro gly pro pro gly glu arg gly his pro gly 645
GTT CCA GGC CAC CCA GGT GTG AGG GGC CCT GAT GGC TTA AAG GGT
val pro gly his pro gly val arg gly pro asp gly leu lys gly 660
CAG AAA GGT GAC ACA ATT TCT TGC AAC GTA ACC TAC CCT GGG AGG
gln lys gly asp thr ile ser cys asn val thr tyr pro gly arg 675
CAT GGC CCT CCA GGT TTT GAT GGA CCT CCA GGT CCG AAG GGA TTT
his gly pro pro gly phe asp gly pro pro gly pro lys gly phe 690
CCA GGT CCC CAA GGT GCC CCT GGG CTG AGT GGT TCA GAT GGG CAT
pro gly pro gln gly ala pro gly leu ser gly ser asp gly his 705
AAA GGC AGA CCT GGC ACA CCA GGA ACA GCG GAA ATA CCA GGT CCA
lys gly arg pro gly thr pro gly thr ala glu ile pro gly pro 720
CCT GGT TTT CGT GGT GAC ATG GGA GAT CCG GGT TTT GGA GGT GAA
pro gly phe arg gly asp met gly asp pro gly phe gly ala glu 735
AAG GGG TCC TCC CCT GTT GGG CCC CCA GGC CCT CCC GGC TCA CCA
lys gly ser ser pro val gly pro pro gly pro pro gly ser pro 750
GGA GTG AAT GGT CAG AAA GGA ATC CCG GGA GAC CCT GCA TTT GGT
gly val asn gly gln lys gly ile pro gly asp pro ala phe gly 765
CAC CTG GGA CCC CCG GGA AAG AGG GGT CTT TCA GGA GTG CCA GGG
his leu gly pro pro gly lys arg gly leu ser gly val pro gly 780
ATA AAA GGA CCC AGA GGT GAT CCG GGA TGT CCA GGG GCT GAA GGG
ile lys gly pro arg gly asp pro gly cys pro gly ala glu gly 795
CCA GCT GGC ATT CCT GGA TTC CTA GGT CTC AAA GGT CCC AAA GGC
pro ala gly ile pro gly phe leu gly leu lys gly pro lys gly 810
AGA GAG GGA CAT GCT GGG TTT CCA GGT GTC CCA GGT CCA CCT GGC
arg glu gly his ala gly phe pro gly val pro gly pro pro gly 825
CAT TCC TGT GAA AGA GGT GCT CCA GGG ATA CCA GGG CAA CCG GGA
his ser cys glu arg gly ala pro gly ile pro gly gln pro gly 840
CTC CCT GGG TAT CCA GGT AGC CCA GGT GCT CCA GGT GGG AAA GGA
leu pro gly tyr pro gly ser pro gly ala pro gly gly lys gly 855
CAG CCG GGA GAT GTG GGG CCT CCC GGG CCA GCT GGA ATG AAA GGC
gln pro gly asp val gly pro pro gly pro ala gly met lys gly 870
CTC CCC GGA CTC CCA GGA CGG CCT GGG GCA CAT GGT CCC CCA GGC
leu pro gly leu pro gly arg pro gly ala his gly pro pro gly 885
CTC CCA GGA ATC CCA GGT CCC TTT GGA GAT GAT GGG CTA CCT GGT
leu pro gly ile pro gly pro phe gly asp asp gly leu pro gly 900
CCT CCA GGT CCA AAG GGA CCC CGG GGG CTG CCT GGT TTC CCA GGT
pro pro gly pro lys gly pro arg gly leu pro gly phe pro gly 915
TTT CCC GGA GAA AGA GGA AAG CCT GGT GCA GAG GGA TGT CCT GGC
phe pro gly glu arg gly lys pro gly ala glu gly cys pro gly 930
GCA AAG GGA GAA CCT GGA GAG AAG GGC ATG TCT GGC CTT CCT GGA
ala lys gly glu pro gly glu lys gly met ser gly leu pro gly 945
GAC CGG GGA CTG AGA GGG GCC AAA GGA GCC ATA GGA CCT CCC GGA
asp arg gly leu arg gly ala lys gly ala ile gly pro pro gly 960
GAT GAA GGA GAA ATG GCT ATC ATT TCA CAA AAG GGA ACA CCT GGG
asp glu gly glu met ala ile ile ser gln lys gly thr pro gly 975
GAA CCT GGA CCT CCT GGA GAT GAT GGA TTC CCA GGA GAA AGA GGT
glu pro gly pro pro gly asp asp gly phe pro gly glu arg gly 990
GAT AAA GGA ACT CCC GGG ATG CAA GGG AGA AGA GGA GAG CTG GGA
asp lys gly thr pro gly met gln gly arg arg gly glu leu gly 1005
AGA TAC GGA CCA CCT GGA TTT CAC AGA GGG GAA CCT GGT GAG AAA
arg tyr gly pro pro gly phe his arg gly glu pro gly glu lys 1020
GGT CAG CCA GGG CCT CCT GGA CCC CCA GGC CCT CCA GGC TCA ACT
gly gln pro gly pro pro gly pro pro gly pro pro gly ser thr 1035
GGT CTA AGA GGG TTC ATT GGT TTT CCA GGA CTT CCA GGT GAC CAG
gly leu arg gly phe ile gly phe pro gly leu pro gly asp gln 1050
GGT GAG CCA GGT TCT CCA GGT CCC CCT GGA TTT TCA GGA ATT GAT
gly glu pro gly ser pro gly pro pro gly phe ser gly ile asp 1065
GGA GCA AGA GGA CCT AAA GGA AAC AAA GGT GAC CCT GCC AGT CAC
gly ala arg gly pro lys gly asn lys gly asp pro ala ser his 1080
TTT GGT CCA CCT GGT CCA AAG GGT GAG CCA GGT AGC CCT GGA TGT
phe gly pro pro gly pro lys gly glu pro gly ser pro gly cys 1095
CCA GGG CAT TTT GGA GCA TCC GGA GAG CAG GGC TTG CCT GGT ATT
pro gly his phe gly ala ser gly glu gln gly leu pro gly ile 1110
CAA GGG CCC AGA GGA TCA CCT GGA AGG CCA GGG CCA CCT GGC TCC
gln gly pro arg gly ser pro gly arg pro gly pro pro gly ser 1125
TCT GGA CCA CCA GGG TGC CCA GGT GAT CAC GGG ATG CCT GGG CTG
ser gly pro pro gly cys pro gly asp his gly met pro gly leu 1140
AGG GGA CAG CCA GGA GAA ATG GGA GAC CCT GGG CCA AGA GGC CTC
arg gly gln pro gly glu met gly asp pro gly pro arg gly leu 1155
CAG GGG GAT CCA GGG ATA CCA GGT CCT CCG GGA ATA AAA GGT CCC
gln gly asp pro gly ile pro gly pro pro gly ile lys gly pro 1170
TCC GGA TCA CCT GGC CTG AAC GGC TTG CAT GGA TTG AAA GGT CAG
ser gly ser pro gly leu asn gly leu his gly leu lys gly gln 1185
AAA GGA ACT AAA GGT GCT TCA GGT TTG CAT GAT GTG GGG CCA CCT
lys gly thr lys gly ala ser gly leu his asp val gly pro pro 1200
GGT CCA GTG GGA ATA CCT GGG CTA AAA GGG GAG AGA GGA GAC CCT
gly pro val gly ile pro gly leu lys gly glu arg gly asp pro 1215
GGG AGC CCA GGA ATC TCT CCT CCA GGT CCT CGT GGA AAG AAA GGT
gly ser pro gly ile ser pro pro gly pro arg gly lys lys gly 1230
CCC CCA GGA CCC CCA GGG AGT TCA GGA CCA CCT GGT CCT GCA GGT
pro pro gly pro pro gly ser ser gly pro pro gly pro ala aly 1245
GCC ACA GGA AGA GCT CCT AAG GAC ATT CCT GAC CCG GGT CCA CCT
ala thr gly arg ala pro lys asp ile pro asp pro gly pro pro 1260
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