Gene: [00.0/ATIC] 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT; EC:2.1.2.3); IMP cyclohydrolase (IMPCHASE; 3.5.4.10); AICARFT/IMPCHASE;
FUN |
AICARFT (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase) and IMPCHase (IMP cyclohydrolase) catalyze the penultimate and final steps, respectively, of the de novo purine biosynthetic pathway (Rayl-1996)." |
REF |
CLO,SEQ,EXP,DOM "Rayl EA &: JBC, 271, 2225-2233, 1996 |
CLA |
coding, basic |
LOC |
RS |
MIM |
MIM: 601731 |
EZN |
ENZYME: 2.1.2.3 |
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