Gene: [00.0/FDPS] farnesyldiphosphate synthetase (dimethylallyltransferase; EC:2.5.1.1); farnesyldiphosphate synthetase (geranyl-trans-transferase; EC:2.5.1.10);


COM

This enzyme has another (synonymous) name: farnesylpyrophosphate synthetase."

FUN

The functionally active enzyme participates in synthesis of polyprenoid compounds and eventually in the lipid turnover."

FAG

At least five FDPS copies are revealed in the genome. They are mapped to chrs 1q, 7, 14, 15q, and Xq (GEM:01q/FDPSL1; GEM:07^/FDPSL2; GEM:14^/FDPSL3; GEM:15q/FDPSL4; and GEM:0Xq2/FDPSL5, respectively). It is not known yet, which of them is the active gene and which are pseudogenes."

REF

PRO,COD,EAG "Heinzmann C &: Genomics, 5, N3, 493-500, 1989

SWI

SWISSPROT: P14324

KEY

lip

CLA

coding, basic

LOC

RS

MIM

MIM: 134629

EZN

ENZYME: 2.5.1.1

Смотрите также:

  • диметилаллилтрансфераза-HUGEN