Gene: [00.0/FYB] FYN-binding protein (FYB-120/130; SLAP-130); [SLAP130 ]
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FUN |
The FYN-binding protein is involoved in T-cell receptor signaling via activation of the src protein-tyrosine kinases LCK (GEM:01p3/LCK) and FYN (GEM:06q21/FYN) (Da Silva-1993). FYB acts as a component of the FYN and SLP76 signaling cascades in T cells (Da Silva-1997b)." |
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REF |
CLO,SEQ,EXP "da Silva AJ &: PNAS, 94, N14, 7493-7498, 1997a EXP,FUN "da Silva AJ &: J Immunol, 158, 2007-2016, 1997b EXP,FUN "da Silva AJ &: J Exp Med, 178, 2107-2113, 1993 CLO,SEQ,EXP "Musci MA &: JBC, 272, N18, 11674-11677, 1997 |
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KEY |
imm |
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CLA |
coding, basic |
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LOC |
RS |
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MIM |
MIM: 602731 |
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SYN |
SLAP130 |
