Gene: [00.0/GRB7] growth factor receptor-bound protein 7;


FAG

The adapter subclass of src homology (SH)2 domain-containig proteins consists largely of noncatalytic protein modules and functions downstream of tyrosine kinases, linking receptors or other tyrosine phosphorylated proteins to separate effectors (Pawson-1995; Baker-1996). See GEM:17q2/GRB2; GEM:00.0/GRB10; GEM:02q2/GRB14."

REF

FAG "Baker E &: Genomics, 36, 218-220, 1996
REV,FUN,FAG "Pawson T: Nature, 373, 573-580, 1995

KEY

sign

CLA

coding, basic

LOC

RS ? 17 q

MIM

MIM: 601522