Gene: [00.0/NRXN1] neurexin I alpha/beta;


COM

Neurexins (see also GEM:00.0/NRXN2 and GEM:00.0/NRXN3) are polymorphic cell surface proteins that are expressed in neurons (Ushkaryov-1992). Each neurexin gene has 2 independent promoters which generate 2 classes of mRNAs: the longer mRNAs encode alpha-neurexins and the shorter mRNAs encode beta-neurexins (Ichtchenko-1995). The the total number of neurexin isoforms in brain probably exceeds 2,000 (Ullrich-1995)."

REF

COD,SEQ "Ichtchenko K &: Cell, 81, 435-443, 1995
FUN "Krasnoperov VG &: BBRC, 227, 868-875, 1996
FUN,EXP,TIS "Ullrich B &: Neuron, 14, 497-507, 1995
CLO,SEQ "Ushkaryov YA &: JBC, 269, 11987-11992, 1994
CLO,RAT "Ushkaryov YA &: Science, 257, 50-56, 1992

KEY

neu, mem

CLA

coding, basic

LOC

RS

MIM

MIM: 600565