Gene: [00.0/RNASE1] ribonuclease, RNase A family, 1 (pancreatic);


COM

Elliott-1986 localized murine ribonuclease gene to Chr 14 and suggested the location of human RIB homologue in Chr 14 too, however this hypothesis has not yet been confirmed."

FUN

Pancreatic ribonuclease (EC 3.1.27.5) is one of the digestive enzymes secreted in abundance by the pancreas; it catalyzes endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates."

REL

GEM:14q/RNASE2; GEM:14q/RNASE3; GEM:14^/RNASE4; GEM:14^/RNASE6; 01q25/RNASEL; GEM:04q31/RNASELI."

REF

COM,LOC,EAG,MOU "Elliott RW &: CCG, 42, N1-2, 110-112, 1986
SEQ "Haugg M, Schein CH: NAR, 20, 612-612, 1992
SEQ "Seno M &: BBA, 1218, 466-468, 1994

SWI

 SWISSPROT: P07998

KEY

git, nucm

CLA

coding, basic

LOC

RS ? 14

MIM

 MIM: 180440

EZN

 ENZYME: 3.1.27.5