Gene: [00.0/SLC5A5] solute carrier family 5 (sodium iodide symporter), member 5; hypothyroidism, congenital (due to sodium iodide symporter defect); thyroid hormonogenesis, genetic defect in, I (MIM:274400); [NIS ]

FUN	The SLC5A5 gene product is a sodium-iodide symporter and actively transports iodide across the basolateral plasma membrane of the thyroid follicular cells."
REF	PAT,MUT,FOG "Fujiwara H &: Nature Genet, 16, N2, 124-125, 1997 COD,SEQ,EVO "Smanik PA &: BBRC, 226, N2, 339-345, 1996
KEY	horm, trp, ion, mem
CLA	coding, basic
LOC	RS
MIM	MIM: 601843
SYN	NIS