Gene: [01p31/MSH4] mutS (E. coli) homolog 4;


COM

By fluorescence in situ hybridization, the MSH4 gene was mapped to Chr 1p31 (Paquis-Flucklinger-1997)."

FUN

In Saccharomyces cerevisiae, MSH4 is a meiosis-specific protein that is not involved in mismatch correction as in E.coli. This protein is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I."

MOP

The predicted human 936-amino acid sequence shows 28.7% identity with the S. cerevisiae MSH4 protein (Paquis-Flucklinger-1997)."

REF

COD,SEQ,EXP,EVO,LOC "Paquis-Flucklinger V &: Genomics, 44, N2, 188-194, 1997

KEY

onc, git

CLA

coding, basic

LOC

01 p31

MIM

MIM: 602105

鸯铗痂蝈 蜞赕:

  • Gene: [02p16/MSH2] mutS (E. coli) homolog 2; colon cancer, nonpolyposis type 1; [COCA1]