Gene: [01p3/SDHB] succinate dehydrogenase complex, subunit B, iron sulphur (Ip) subunit;
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COM |
Another code, EC:1.3.5.1, is also used in literature and SWISSPROT. This code denotes the succinate dehydrogenase complex that reacts with ubiquinone and apparently contains the product of this gene." |
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MOP |
SDH is a Fe-containing flavoprotein. It is the only insoluble enzyme of the citric acid (Krebs) cycle and, as a result, is rigidly bound with the inner mitochondrial membrane. Its activity is accounted for by two peptides (MM 70 and 30 kD); it is currently unknown whether they are encoded by different loci or the same locus." |
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FUN |
[1] SDH is an enzyme of the citric acid cycle.
[2] Systematic name: succinate:acceptor oxidoreductase Catalyzed reaction: succinate + acceptor = fumarate + reduced acceptor. [3] SDH can be incorporated into a succinate dehydrogenase complex (EC:1.3.5.1), acquiring the ability to react with ubiquinone. Systematic name: succinate:ubiquinone oxidoreductase Catalyzed reaction: succinate + ubiquinone = fumarate + ubiquinol." |
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REF |
LOC,MAP "Au HC &: Gene, 159, 249-253, 1995 LOC,MAP "Cook PJ, Hamerton JL: CCG, 32, (HGM6), 111-120, 1982 LOC,MAP "Leckschat S &: Somat Cell Mol Genet, 19, 505-511, 1993 LOC,MAP "Mascarello JT &: CCG, 28, 121-135, 1980 |
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KEY |
mito, cytr |
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CLA |
coding, basic |
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LOC |
01 p36-35 |
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MIM |
MIM: 185470 |
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EZN |
ENZYME: 1.3.99.1 |
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