Gene: [01p/BRDT] bromodomain-containing, testis-specific protein;
|
SUM |
[1] The bromodomain is a motif of 59 to 63 amino acids thought to be
involved
in protein-protein interaction. It is found in proteins that regulate
transcription. Northern analysis of 16 normal tissues and 8 cancer cell
lines showed BRDT transcripts of 3.5 and 4.0 kb expressed specifically in
testis. PCR analysis of a panel of monochromosomal human/rodent hybrid
cell lines and a Genebridge4 panel of radiation hybrids localized the
gene to 1p (Jones-1997).
[2] A study of cDNA clones indicated that the gene encodes a protein of 947 amino acids with extensive homology to RING3 and to the Drosophila developmental gene fsh (Jones-1997)." |
|
REF |
COD,SEQ,LOC,EVO "Jones MH &: Genomics, 45, 529-534, 1997 |
|
KEY |
trc |
|
CLA |
coding, basic |
|
LOC |
01 p |
|
MIM |
MIM: 602144 |
