Gene: [01q4/ADPRT] poly(ADP-ribose) polymerase (NAD+:ADP-ribosyltransferase);


FUN

The reaction catalyzed: NAD+ + (ADP-D-ribosyl)(n)-acceptor = = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor."

FAG

Two pseudogenes have been found (GEM:13q34/ADPRTP1 and GEM:14q/ADPRTP2)."

REF

PRO,COD,SEQ,EXP,MOP "Alkhatib &: PNAS, 84, N5, 1224-1228, 1987
PRO,SEQ,LOC,FAG "Cherney BW &: PNAS, 84, N23, 8370-8374, 1987
PRO,SEQ,LOC,FAG "Herzog H &: PNAS, 86, 3514-3518, 1989
PRO,SEQ,LOC,FAG "Herzog H &: Biol Chem Hoppe-Seyler, 369, 836-837, 1988
PRO,COD,SEQ,EXP,MOP "Kurosaki T &: JBC, 262, 15990-15997, 1987
FUN,MOP,EXP "Loetscher &: PNAS, 84, N5, 1286-1289, 1987
LOC,PRO,FAG "McBride OW &: CCG, 46, (HGM9), 659-660, 1987
COD,PRO "Schneider R &: Eur J Cell Biol, 44, 302-307, 1987
LOC,PRO "Zabel &: CCG, 51, (HGM10), 1115, 1989

SWI

SWISSPROT: P09874

KEY

nucm, trc

CLA

coding, basic

LOC

01 q41-42

MIM

MIM: 173870

EZN

ENZYME: 2.4.2.30

鸯铗痂蝈 蜞赕:

  • Gene: [04q34/CASP3] caspase 3, apoptosis-related cysteine protease; apopain (PARP cleavage protease);