Gene: [02p12/IGKVO9] immunoglobulin, kappa VAR-region, group I/O, polypeptide 9;


FAG

 As it follows from the data of Straubinger-1988, O and A fragments (for more details, see FAM:IGK/02p12) overlap at a/b clusters; as a result, Vk genes A15 and A16 are in fact genes O9 and O10, respectively. For this reason, genes IGKVA(15,16) are not indicated in the GEM catalogue."

MAF

 Fragment O of the IGKV locus comprises 210 kb and contains 18 Vk genes (or pseudogenes)."

REF

 PRO,SEQ,MAF,EXP "Pohlenz HD &: J Mol Biol, 193, 241-253, 1987
PRO,SEQ,MAF,EXP "Straubinger B &: J Mol Biol, 199, 23-34, 1988

KEY

 imm, img

CLA

 coding, basic

LOC

 02 p12

MIM

 MIM: 146980?

Смотрите также:

  • Gene: [02p12/IGKVO10] immunoglobulin, kappa VAR-region, group x/O, polypeptide 10;