Gene: [02p1/CDK7] cyclin-dependent kinase 7 (42kD; homolog of Xenopus MO15 cdk-activating kinase); serine/threonine kinase 1;


FAG

[1] The mammalian CDK-activating kinase (CAK) is composed of 2 major polypeptides, cyclin H (GEM:05q1/CCNH), and CDK7 kinase (Fisher-1994). Shiekhattar-1995 gave evidence that CAK complex is a component of transcription factor TFIIH (see GEM:11p1/GTF2H1).
[2] On other serine/threonine kinases see GEM:03p211/STK2, GEM:00.0/STK3, GEM:00.0/STK4, and GEM:20q13/STK6."

REF

CLO,SEQ "Darbon J-M &: Oncogene, 9, 3127-3138, 1994
CLO,SEQ "Fisher RP, Morgan DO: Cell, 78, 713-724, 1994
CLO,SEQ,LOC "Levedakou EN &: Oncogene, 9, 1977-1988, 1994
FUN "Shiekhattar R &: Nature, 374, 283-287, 1995
CLO,SEQ "Tassan J-P &: J Cell Biol, 127, 467-478, 1994
CLO,SEQ "Wu L &: Oncogene, 9, 2089-2096, 1994

SWI

SWISSPROT: P50613

KEY

ont, pep

CLA

coding, basic

LOC

02 p15-c

MIM

MIM: 601955

EZN

ENZYME: 2.7.1.?

鸯铗痂蝈 蜞赕:

  • Gene: [12q13/CDK2] cyclin-dependent kinase 2 (p34; homolog of Xenopus Eg1);