Gene: [02q333/IDH1] isocitrate dehydrogenase 1 (NADP+), soluble;
|
COM |
HGM indicates a less definite location for IDH1: 2q32-qt. |
|
FAG |
A mitochondrial isoform is encoded by the nuclear gene mapped in Chr 15q2 (GEM:15q2/IDH2). See also GEM:15q25/IDH3A; GEM:00.0/IDH3B; GEM:0Xq28/IDH3G." |
|
FUN |
The catalyzed reaction: isocitrate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH." |
|
REF |
FUN,FOG "Chen &: AJHG, 24, 325-329, 1972 LOC "Creagan &: AJHG, 26, 604-613, 1974 LOC "Hamerton JL &: AJHG, 27, 595-608, 1975 LOC "Narahara K &: Hum Genet, 71, 37-40, 1985 LOC "Weil &: Hum Genet, 36, 205-211, 1977 |
|
KEY |
cytr |
|
CLA |
coding, basic |
|
LOC |
02 q33.3 |
|
MIM |
MIM: 147700 |
|
EZN |
ENZYME: 1.1.1.42 |
