Gene: [02q33/CD28] antigen CD28 (Tp44; T-cell-specific);
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EAG |
Genes CD28 and linked to it CTLA4 (GEM:02q33/CTLA4) are components of superfamily of immunoglobulin-like genes (FAM:IMM/00.0) and form a subgroup of membrane-bound single domains V (Lafage-Pochitaloff-1990). CD28 and CTLA4 are thought to have appeared as a result of duplication of a single precursor and hence might have common functions." |
|
REF |
COD,EXP,TRC "Gehr, Leslauer: Experientia, 46, 56, 1990 LOC,LIN "Lafage-Pochitaloff M &: Immunogenetics, 31, N3, 198-201, 1990 |
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KEY |
imm, img, mem |
|
CLA |
coding, basic |
|
LOC |
02 q33 |
|
MIM |
MIM: 186760 |
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