Gene: [02q33/CD28] antigen CD28 (Tp44; T-cell-specific);


EAG

Genes CD28 and linked to it CTLA4 (GEM:02q33/CTLA4) are components of superfamily of immunoglobulin-like genes (FAM:IMM/00.0) and form a subgroup of membrane-bound single domains V (Lafage-Pochitaloff-1990). CD28 and CTLA4 are thought to have appeared as a result of duplication of a single precursor and hence might have common functions."

REF

COD,EXP,TRC "Gehr, Leslauer: Experientia, 46, 56, 1990
LOC,LIN "Lafage-Pochitaloff M &: Immunogenetics, 31, N3, 198-201, 1990

KEY

imm, img, mem

CLA

coding, basic

LOC

02 q33

MIM

MIM: 186760

鸯铗痂蝈 蜞赕:

  • Gene: [03q21/CD86] CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); antigen CD28 ligand 2 (T lymphocyte activation antigen CD86; antigen B7-2); [CD28LG2 ]
  • Gene: [03q21/CD80] CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); antigen CD28 ligand 1 (T lymphocyte activation antigen CD80; antigen B7-1); [CD28LG1 ]
  • HUGEN-CD28