Gene: [02q3/CHRND] cholinergic receptor, nicotinic, delta polypeptide (muscle); [ACHRD ]
ASS | It is known that in autoimmune disease, myasthenia gravis (MG), antibodies against cholinergic receptors are found, the number of receptors decreasing gradually with the progression of the pathology. The MIM Catalogue describes different MG forms under the numbers MIM:254200 (the secondary marker) and MIM:254210. The gene that accounts for the liability to MG is most probably linked to MHC complex in chromosome 6p (as is the case for a number of other autoimmune diseases, the general liamility to which is described under MIM 109100)." |
FAG | See GEM:02q32/CHRNA1. |
REF | PRO,LOC,MOL,FAG
"Beeson &: CCG, 51, (HGM10), 960, 1989 EAG,MAP "Heidmann O &: Science, 234, 866-888, 1986 PRO,LOC,PAG "Lobos EA &: AJHG, 44, 522-533, 1989 |
SWI | SWISSPROT: Q07001 |
KEY | neu, myo, mem, recp |
CLA | coding, basic |
LOC | 02 q36-37 |
MIM | MIM: 100720 |
SYN | ACHRD |
