Gene: [02q3/IHH] Indian hedgehog (Drosophila) homolog;


COM

IHH gene was assigned to chromosome 2 with the use of PCR analysis of DNA from a panel of rodent/human somatic cell hybrids (Marigo-1995). Using fluorescence in situ hybridization, Leek et al. (Leek-1997) regionalized the assignment to 2q33-q35."

FAG

There are 3 known mammalian homologs of the Drosophila gene 'hedgehog' (hh) that encodes inductive signals during embryogenesis: Indian hedgehog (Ihh), sonic hedgehog (Shh, GEM:07q36/SHH), and desert hedgehog (Dhh)."

REF

FAG "Echelard Y &: Cell, 75, 1417-1430, 1993
LOC "Leek JP &: CCG, 76, 187-188, 1997
CLO,SEQ,EXP,LOC,FAG "Marigo V &: Genomics, 28, 44-51, 1995
FAG "Roelink H &: Cell, 76, 761-775, 1994

KEY

bone

CLA

coding, basic

LOC

02 q33-q35

MIM

MIM: 600726