Gene: [03p211/ALAS1] delta-aminolevulinate synthase 1 (housekeeping);
|
FUN |
Systematic name: succinyl-CoA:glycine C-succinyl-transferase (decarboxylating). The reaction catalyzed: succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO(2). Cofactor: piridoxalephosphate." |
|
FAG |
Gene for other isoform has been mapped: GEM:0Xp1121/ALAS2. |
|
PRO |
Probe pGEM-1 (a 1.7 kb cDNA fragment) was cloned at EcoRI site in plasmide pUC?" |
|
REF |
LOC,PRO "Astrin &: CCG, 46, (HGM9), 573, 1987 PRO,SEQ,EXP "Bawden MJ &: NAR, 15, 8563, 1987 CLO,SEQ "Bishop DF: NAR, 18, 7187-7187, 1991 CLO,LOC "Bishop DF &: Genomics, 7, 207-214, 1990 CLO,LOC "Cotter PD &: CCG, 69, 207-208, 1995 LOC,PRO "Sutherland GR &: AJHG, 43, 331-335, 1988 |
|
KEY |
mito, aac, lip |
|
CLA |
coding, basic |
|
LOC |
03 p21.1 |
|
MIM |
MIM: 125290 |
|
EZN |
ENZYME: 2.3.1.37 |
