Gene: [03p2/PLCD1] phospholipase C, delta 1;
COM | Ishikawa-1997 narrowed the PLCD1 assignment to Chr 3p22-21.3 . |
MOP | The PLCD1 peptide sequence is distinguished from PLCG by lack of the SH2 and SH3 domains that are essential for activation of PLC-gamma (see GEM:20q1/PLCG1) by tyrosine protein kinases, and from PLC-beta (see GEM:00.0/PLCB2) by lack of the C-terminal region of PLC-beta that is responsible for binding and activation by G proteins (Cheng-1995)." |
REL | GEM:11q13/PLCB3; GEM:20p12/PLCB4; GEM:02q33/PLCE; GEM:20q1/PLCG1; GEM:16q241/PLCG2. See also GEM:03q2/PLD1." |
REF | CLO,SEQ "Cheng HF &:
JBC, 270, 5495-5505, 1995 GEN,LOC "Ishikawa S &: CCG, 78, 58-60, 1997 LOC,FAG,EAG "Lyu MS &: Mammal Genome, 7, 501-504, 1996 |
SWI | SWISSPROT: P51178 |
KEY | lip |
CLA | coding, basic |
LOC | 03 p22-21.3 |
MIM | MIM: 602142 |
EZN | ENZYME: 3.1.4.11 |
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