Gene: [03q13/MOX2] antigen MOX2 (monoclonal antibody MRC-OX2); MRC OX-2 membrane glycoprotein; [MOX1 ]


FUN

Specific function is not known yet.

IDN

The antigen was identified using murine monoclonal antibodies against the membrane proteins of rat T lymphocytes."

MOP

Two isoforms are known, the thymocytic one with MM 47 kD and the cerebral one with MM 41 kD, which differ in the proportion of glycosilated amino acid residues (33 and 24%, respectively). The polypeptide translation product contains 248 amino acids, 202 C-terminal ones forming the extracellular part consisting of two domains. These domains have a structure similar to that of immunoglobulin peptides."

PRO

Gene-specific DNA probe HX2/HIII (a 3.8 kb fragment) has been cloned at HindIII site in the plasmid pUC18."

POL

EcoRI A-RFLP (Douglas-1988; Probe [1]): allele A1= 6.8 kb/(popul freq= 0.62); allele A2= 3.8/(0.38)"

REF

PRO,POL "Douglas J &: NAR, 16, 9067, 1988
FUN,CLO,SEQ,MOP,LOC "McCaughan GW &: Immunogenetics, 25, 133-135, 1987

SWI

SWISSPROT: P41217

KEY

mem, img

CLA

coding, basic

LOC

03 q13

MIM

MIM: 155970

SYN

MOX1