Gene: [05q1/NRPB] nuclear restricted protein, BTB domain-like (brain); [PIG10 ]
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SUM |
NRPB is a novel nuclear matrix protein, specifically expressed in primary neurons, that interacts with p110 (hypophosphorylated form of retinoblastoma protein, see GEM:13q142/RB1) and participates in the regulation of neuronal process formation. NRPB contains two major structural elements: a BTB domain-like structure in the predicted NH2 terminus, and a "kelch motif" in the predicted COOH-terminal domain. NRP/B mRNA (5.5 kb) is predominantly expressed in human fetal and adult brain with minor expression in kidney and pancreas (Kim-1998)." |
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REF |
CLO,LOC "Kim TA &: J Cell Biol, 141, 553-566, 1998 |
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KEY |
neu |
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CLA |
coding, basic |
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LOC |
05 q12-13.3 |
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MIM |
? |
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SYN |
PIG10 |
