Gene: [05q35/NPM1] nucleophosmin (nucleolar phosphoprotein B23, numatrin); non-Hodgkin's lymphoma with t(2;5)(p23;q35); myelodysplastic syndrome and acute myeloid leukemia with t(3;5)(q25.1;q35);
FAG | [1] NMP1
fuses to the anaplastic lymphoma kinase (GEM:02p23/ALK) in non-Hodgkin's lymphoma with
t(2;5)(p23;q35) chromosomal translocation (Morris-1994). [2] NMP1 fuses to the myeloid leukemia factor 1 (GEM:03q251/MLF1) in myelodysplastic syndrome and acute myeloid leukemia with t(3;5)(q25.1;q35) chromosomal translocation (Yoneda-Kato-1996)." |
PSG | GEM:00.0/NPMP1; GEM:00.0/NPMP2; GEM:00.0/NPMP3; GEM:00.0/NPMP4; GEM:00.0/NPMP5; GEM:00.0/NPMP6; GEM:00.0/NPMP7." |
REF | CLO,SEQ,EXP "Chan WY
&: Biochemistry, 28, 1033-1039, 1989 CLO,SEQ,EXP "Liu QR &: DNA Cell Biol, 12, 149-156, 1993 LOC,ABR "Morris SW &: Science, 263, 1281-1284, 1994 LOC,ABR "Yoneda-Kato N &: Oncogene, 12, 265-275, 1996 |
SWI | SWISSPROT: P06748 |
KEY | onc |
CLA | coding, basic |
LOC | 05 q35 |
MIM | MIM: 164040 |
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