Gene: [06p2131/MLN] motilin (gastrointestinal hormone);


GEN

[1] The gene length: 9.3 kb; exons: 5; introns: 4 (2.7; 1.7; 3.5; 0.7 kb).
[2] The processed trancript (0.7 kb) contains 5'-unt (untranslated), 72-bp region and the following areas: the signal peptide (25 amino acid residues), the motilin itself (22 amino acid residues), the C-terminal peptide (83 amino acids), which function is currently unclear, and the 3'-unt region (155 bp). All these areas are coded by five exons, the motilin, in particular, being coded by the 3'-half of 2nd exon and by the 5'-half of 3d one. Its amino acid sequence is the following: FVPIFTYGELQRMQEKERNKGQ."

REF

PRO,SEQ,EXP,EVO "Bond &: Mol Endocrinol, 2, 175-180, 1988
IDN,PEP,VER "Brown &: Gastroenterology, 62, 401-404, 1972
GEN,STR,MOP,EXP "Daikh DI &: DNA, 8, 615-621, 1989
LOC,CYG,MOL "Fan &: CCG, 51, (HGM10), 997, 1989
PEP,FUN "Itoh &: Scand J Gastroenterol, 11, (Suppl 39), 93-110, 1976
PEP,FUN "Rennie &: Gut, 20, A912, 1979
IDN,PEP,VER "Schubert, Brown: Can J Biochem, 52, 7-8, 1974
PRO,SEQ,EXP,EVO "Seino Y &: FEBS Lett, 223, 74-76, 1987
GEN,STR,MOP,EXP,LOC "Yano H &: FEBS Lett, 249, N2, 248-252, 1989

KEY

git, horm

CLA

coding, basic

LOC

06 p21.31

MIM

MIM: 158270

鸯铗痂蝈 蜞赕:

  • 填蜩腓