Gene: [06p21/MEP1A] meprin A, alpha (PABA peptide hydrolase);


MOP

Meprin A contains both alpha and beta subunits and is present in the kidney of rats and some strains of mice and in the rat and human intestine. Meprin B, which contains only beta subunits, is present in the kidney of many inbred mouse strains and in intestine of all mice. Therefore, the differential expression of meprin subunits is a mechanism for regulation of tissue-specific gene expression."

FAG

The gene for beta subunit of meprin is mapped: GEM:18q12/MEP1B.

REF

PRO,LOC,FAG "Bond JS &: Genomics, 25, 300-303, 1995
CLO,SEQ "Dumermuth E &: FEBS Lett, 335, 367-375, 1993
LOC "Jiang W &: BBRC, 216, 630-635, 1995
COD "Jiang W &: JBC, 268, 10380-10385, 1993
PRO,COD,EXP "Jiang W &: JBC, 267, 9185-9193, 1992

KEY

pep

CLA

coding, basic

LOC

06 p21.2-.1

MIM

MIM: 600388

EZN

ENZYME: 3.4.24.18