Gene: [06p241/EDN1] endothelin 1; [ET1 ]


FAG

[1] Three different forms of structurally and functionally homologous peptides, endothelins 1, 2, and 3, are currently identified. All the three genes are mapped, see GEM:01p34/EDN2, GEM:20q13/EDN3.
[2] Two endothelin receptors are mapped (see 04^/EDNRA and 13q22/ENDRB)."

REF

CLO,COD,LOC,FAG "Arinami &: AJHG, 48, N5, 990-996, 1991
CLO,PRO,LOC,MOL "Bloch KD &: JBC, 264, 10851-10857, 1989
EXP "Giaid A &: PNAS, 86, N18, 7634-7638, 1989
CLO,COD,SEQ,EXP "Inoue A &: JBC, 264, 14954-14959, 1989a
CLO,COD,PEP,SEQ,EVO,FAG "Inoue A &: PNAS, 86, N8, 2863-2867, 1989b

KEY

card, horm

CLA

coding, basic

LOC

06 p24.1

MIM

MIM: 131240

SYN

ET1

鸯铗痂蝈 蜞赕:

  • ET1 (蓓漕蝈腓-1)
  • Gene: [01p36/ECE1] endothelin converting enzyme 1;
  • Gene: [03q21/GATA2] GATA-binding protein 2 (endothelial transcription factor; p45);
  • Gene: [04^/EDNRA] endothelin receptor type A (endothelin 1 receptor);