Gene: [08p11/MOZ] monocytic leukaemia zinc finger protein (acetyltransferase?); monocytic leukaemia?;


MOP

The MOZ gene encodes a predicted 2,004-amino acid, 225-kD polypeptide with 2 bipartite nuclear localization domains. MOZ is a founding member of a group of highly conserved proteins characterized by a single C2HC3 zinc finger in conjunction with a putative acetyltransferase consensus domain. MOZ also contains two C4HC3 zinc finger domains, protein interaction motifs associated with chromatin-bound proteins. These motifs suggested to Borrow-1996 that MOZ may represent a chromatin-bound acetyltransferase."

REF

ABR,LOC "Borrow J &: Nature Genet, 14, 33-41, 1996
COD,LOC,EVO "Schuler GD &: Science, 274, N5287, 540-546, 1996

SWI

 SWISSPROT: Q92794

KEY

ont

CLA

coding, basic

LOC

08 p11.2-.1

MIM

 MIM: 601408