Gene: [08p1/ADRB3] adrenergic, beta-3-, receptor;


FUN

The beta-3-adrenergic receptor, located mainly in adipose tissue, is involved in the regulation of lipolysis and thermogenesis."

ASS

The potential relevance of ADRB3 to obesity in humans, proposed by Clement et al. (Clement-1995), was not confirmed in several studies (Elbein-1996, Gagnon-1996, Elbein-1996, Nagase-1996)."

FAG

See GEM:20^/ADRA1A.

REF

ASS,FUN,MUT "Clement K &: New Engl J Med, 333, 352-354, 1995
ASS,POP,MUT "Elbein SC &: J Clin Endocrinol Metab, 81, 4422-4427, 1996
ASS,POP "Gagnon J &: J Clin Invest, 98, 2086-2093, 1996
ASS,POP,FOG,MUT "Nagase T &: J Clin Endocrinol Metab, 82, 1284-1287, 1997
GEN,SEQ,EVO "Van Spronsen A &: Eur J Biochem, 213, 1117-1124, 1993
LOC,LIN "Wilkie TM &: Genomics, 18, 175-184, 1993

SWI

SWISSPROT: P13945

KEY

neu, recp, mem, sign

CLA

coding, basic

LOC

08 p12-11.1

MIM

MIM: 109691

鸯铗痂蝈 蜞赕:

  • 冷疱眍疱鲥矧铕 徨蜞3