Gene: [08p21/BMP1] bone morphogenetic protein 1 (zinc metalloprotease?); procollagen C-proteinase; tolloid (Drosophila)-like;


FAG

[1] It is assumed that the human genome contains nine BMP genes accounting for the morphogenesis of bone tissue: GEM:08p21/BMP1, GEM:20p12/BMP2, GEM:04^/BMP3, GEM:14q2/BMP4, GEM:06^/BMP5, GEM:06^/BMP6, GEM:20^/BMP7, GEM:00.0/BMP8, and GEM:20q112/CDMP1(BMP9).
[2] In mammals a single BMP1 gene apparently encodes alternatively spliced transcripts not only for BMP1 but also for a longer protein with a domain structure identical to that of the Drosophila dorsal-ventral patterning gene product tolloid (Takahara-1995)."

REF

FUN "Kessler E &: Science, 271, 360-362, 1996
FUN "Reddi AH: Science, 271, 5-6, 1996
PRO,LOC,FAG "Tabas JA &: Genomics, 9, N2, 283-289, 1991
CLO,SEQ,GEN "Takahara K &: Genomics, 29, 9-15, 1995
PRO,FUN,FAG "Wozney JM &: Science, 242, 1528-1534, 1988
LOC "Yoshiura K &: CCG, 64, 208-209, 1993

SWI

SWISSPROT: P13497

KEY

bone, ont

CLA

coding, basic

LOC

08 p21

MIM

MIM: 112264

EZN

ENZYME: 3.4.24.?