Gene: [08q11/SLUG1] neural crest transcription factor SLUG (zinc finger protein);
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COM |
Rhim-1997 assigned the human homolog to Chr 8. By study of radiation cell lines they showed that it is closely linked to marker D8S2090 at cM 66-69, corresponding to cytogenetic region 8q11." |
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FUN |
'Slug,' a zinc finger protein, appears to play an important role in development of neural crest-derived cells (Savagner-1997) especially in the transition of epithelial to mesenchymal characteristics during emigration from the neural tube (Rhim-1997)." |
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REF |
LOC,EAG,EXP,FUN "Rhim H &: Mammal Genome, 8, 872-873, 1997 EXP,FUN "Savagner P &: J Cell Biol, 137, 1403-1419, 1997 |
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KEY |
trc |
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CLA |
coding, basic |
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LOC |
08 q11 |
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MIM |
MIM: 602150 |
