Gene: [08q1/CYP7A1] cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase), polypeptide 1;
FUN | The reaction catalyzed: cholesterol + NADPH + O(2) = = 7-alpha-hydroxycholesterol + NADP(+) + H(2)O." |
REL | FAM:CYP/00.0. |
REF | COD,LOC "Cohen JC &: Genomics, 14, 153-161, 1992 CLO,SEQ "Karam WG &: BBRC, 185, 588-595, 1992 CLO,SEQ "Molowa DT &: Biochemistry, 31, 2539-2544, 1992 GEN,SEQ "Nishimoto M &: BBA, 1172, 147-150, 1993 CLO,SEQ "Thompson JF &: BBA, 1168, 239-242, 1993 GEN,SEQ,NTC,COD "Wang DP, Chiang JYL: Genomics, 20, 320-323, 1994 |
SWI | SWISSPROT: P22680 |
KEY | xen, ats |
CLA | coding, basic |
LOC | 08 q11-12 |
MIM | MIM: 118455 |
EZN | ENZYME: 1.14.13.17 |
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