Gene: [09p13/APAH1] Ap4A hydrolase 1; diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase;
COM | The APAH1 gene was mapped to chromosome 10 by FISH (McLennan-1998). |
FUN | [1] AP4A
hydrolase is the enzyme responsible for maintaining the intracellular level
of the dinucleoside AP4A (diadenosine 5-prime,5-triple
prime-P(1),P(4)-tetraphosphate). [2] APAH1 is suggested to be a candidate tumor suppressor gene because the mammalian AP3A hydrolase gene (GEM:03p142/FHIT) is a possible tumor suppressor gene (McLennan-1998)." |
REF | LOC,MAP "McLennan AG
&: Genomics, 47, 307-309, 1998 CLO,SEQ "Thorne NM &: Biochem J, 311, 717-721, 1995 |
SWI | SWISSPROT: P50583 |
KEY | nucm |
CLA | coding, basic |
LOC | 09 p13 |
MIM | MIM: 602852 |
EZN | ENZYME: 3.6.1.17 |
