Gene: [09p21/CDKN2B] cyclin-dependent kinase inhibitor 2B (p15); multiple tumor suppressor 2; [MTS2 ]
FUN | CDKN2B inhibits cyclin-dependent kinase CDK4 (GEM:12q13/CDK4) and CDK6 (GEM:07^/CDK6)." |
REF | CLO,SEQ,STR "Guan K-L
&: Genes Dev, 8, 2939-2952, 1994 CLO,SEQ,STR "Hannon GJ, Beach D: Nature, 371, 257-261, 1994 CLO,SEQ,STR "Kamb A &: Science, 264, 436-440, 1994 MUT "Liu L &: Oncogene, 11, 405-412, 1995 MUT "Nobori T &: Nature, 368, 753-756, 1994 MUT "Okamoto A &: Cancer Res, 55, 1448-1451, 1995 MUT "Okuda T &: Blood, 85, 2321-2330, 1995 CLO,SEQ,GEN,EXP "Stone S &: Oncogene, 11, 987-991, 1995 |
SWI | SWISSPROT: P42772 |
KEY | nucm, onc, repr |
CLA | coding, basic |
LOC | 09 p21 |
MIM | MIM: 600431 |
SYN | MTS2 |
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