Gene: [0Xp113/UBE1] ubiquitin-activating enzyme E1; A1S9T and BN75 temperature sensitivity complementing;


FUN

The catalyzed reaction: ATP + ubiquitin + protein lysine = AMP + pyrophosphate + protein N-ubiquityllysine."

REL

GEM:03p21/UBE1L; 0Y^/UBE1Y. See also 0Xq2/UBE2A and 15q1/UBE3A.

REF

LOC,CYG,LIN "Brown &: CCG, 51, (HGM10), 970, 1989a
LOC,CYG,LIN "Brown &: CCG, 51, (HGM10), 970-971, 1989b
LOC "Knight JC &: CCG, 71, 155-157, 1995
LOC,LIN,CYG,FUN "Ohtsubo M, Nishimoto: BBRC, 153, 1173-1178, 1988

SWI

SWISSPROT: P22314

KEY

repr, ont

CLA

coding, basic

LOC

0X p11.3

MIM

MIM: 314370

EZN

ENZYME: 6.3.2.19