Gene: [0Yq11/AZF1] azoospermia factor 1; azoospermia factor (Sertoli-cell-only syndrome);
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FAG |
Vogt-1996 found microdeletions in 3 different Yq11 subregions that led to spermatogenesis disruption at different phases of the process. They proposed the presence of 3 spermatogenesis loci in Yq11: AZFa (this locus), AZFb (GEM:0Yq11/AZF2) and AZFc (GEM:0Yq11/AZF3) and that each locus is active during a different phase of male germ cell development." |
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REF |
LOC "Andersson &: Hum Genet, 79, 2-7, 1988 LOC "Chandley AC &: J Med Genet, 26, 145-153, 1989 HET,MUT "Kobayashi K &: Hum Mol Genet, 3, 1965-1967, 1994 LOC "Ma K &: Hum Mol Genet, 1, 29-33, 1992 LOC "Tiepolo L, Zuffardi O: Hum Genet, 34, 119-124, 1976 LOC "Vogt PH &: Hum Mol Genet, 5, 933-943, 1996 LOC "Vogt PH &: Hum Genet, 89, 491-496, 1992 |
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KEY |
sex |
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CLA |
unknown, basic |
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LOC |
0Y q11 |
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MIM |
MIM: 415000 |
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