Gene: [11q14/PRCP] prolylcarboxypeptidase (peptidyl prolylamino acid hydrolase); lysosomal pro-X carboxypeptidase (angiotensinase C);


COM

Wanson-1997 assigned the PCP gene to Chr 11q14 within 700kD of marker D11S901.

FUN

Prolylcarboxypeptidase is a lysosomal enzyme that cleaves COOH-terminal amino acids linked to proline in peptides such as angiotensin II and bradykinin (see GEM:03q27/KNG)."

REF

CLO,SEQ,STR "Tan F &: JBC, 268, 16631-16638, 1993
LOC "Watson B &: Genomics, 44, N3, 365-367, 1997

KEY

lys

CLA

coding, basic

LOC

11 q14

MIM

MIM: 176785

EZN

ENZYME: 3.4.16.2