Gene: [11q2/NCAM1] neural cell adhesion molecule 1 (CD56); [NCAM CD56 ]
MOP | The product is a membrane glycoprotein found in neurons and glial cells. There are several isoforms of it, the main ones weighing 180 kD (a 7.2-kb transcript), 140 kD (a 6.7-kb transcript), and 120 kD. They are products of the alternative splicing of a common precursor." |
EVO | Extracellular N-terminal region of the protein product (about 500 amino acid residues) shows a high homology with proteins of immunoglobulin superfamily." |
REL | GEM:00.0/NCAM2. |
REF | CLO,COD,SEQ,EXP
"Barton CH &: Development, 104, 165-173, 1988 TRC,PEP,MOP,EXP "Cunningham &: Science, 236, 799-806, 1987 SEQ,MOP,EXP,FUN "Dickson G &: Cell, 50, 1119-1130, 1987 ENG,FUN,EXP "Doherty &: J Cell Biol, 109, (Aug), 789-798, 1989 SEQ,MOP,EXP,FUN "Gower HJ &: Cell, 55, 955-964, 1988 MOP,EXP,FUN "Moore &: J Cell Biol, 105, 1377-1386, 1987 LOC,MOL "Nguyen C &: J Cell Biol, 102, 711-715, 1986 MOP,EXP,FUN "Nybroe &: Neurochem Int, 12, 251-262, 1988 MOP,EXP,FUN "Prentice &: EMBO J, 6, N7, 1859-1863, 1987 LOC "Telatar M &: Mammal Genome, 6, 59-60, 1995 POL "Telatar M &: Hum Mol Genet, 3, 842, 1994 TRC,PEP,MOP,EXP "Thompson &: Genes Dev, 3, 348-357, 1989 MOP,EXP,FUN "Walsh FS &: Development, 105, 803-811, 1989 TRC,PEP,MOP,EXP "Walsh FS: Neurochem Int, 12, 262-267, 1988 CLO,COD,SEQ,EXP,LOC "Walsh FS &: Mol Brain Res, 1, 197-200, 1986 |
SWI | SWISSPROT: P13591; NCA2 P13592 |
KEY | neu, img, mem |
CLA | coding, basic |
LOC | 11 q23-24 |
MIM | MIM: 116930 |
SYN | NCAM CD56 |
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