Gene: [12p11/DDX11] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (S.cerevisiae CHL1-like helicase); keratinocyte growth factor regulated gene 2 (KRG2); [CHLR1 KRG2 ]


COM

The DDX11 gene is mapped to chromosome 12 by analysis of somatic cell hybrids and fluorescence in situ hybridization and is separated from DDX12 (GEM:12p13/DDX12) by 8 to 12 Mb (Amann-1996)."

FUN

The DDX11 protein may be involved in cell cycle regulation (Frank-1996).

EXP

DDX11 protein (as well as DDX12, see GEM:12p13/DDX12) was shown to express only in proliferating human cell lines and to be localized to the nucleolus by indirect immunofluorescence (Amann-1997)."

REF

CLO,EXP,FAG "Amann J &: JBC, 272, 3823-3832, 1997
LOC,FAG "Amann J &: Genomics, 32, 260-265, 1996
CLO,EXP,FUN "Frank S, Werner S: JBC, 271, 24337-24340, 1996

KEY

nucm

CLA

coding, basic

LOC

12 p11

MIM

MIM: 601150

SYN

CHLR1 KRG2

Смотрите также:

  • Gene: [02p24/DDX1] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1;