Gene: [12q241/IFNG] interferon, gamma;
GEN | The gene length is 5.1 kb. Exons: 4; introns: 3 (1238/95 and 2422 bp). The polypeptide product consists of 122 amino acid residues (by exons, O, 38, 23, and 61 amino acids)." |
EVO | Gamma interferon does not share homology with alpha and beta interferons and is not a component of their multigene family, which members have no introns (see FAM:IFN9/09p22)." |
FAG | A receptor and a transductor for IFNG are identified; their genes are located in chrs 6q and 21q (GEM:06q24/IFNGR1 and GEM:21q221/IFNGT1)." |
REF | PEP,SEQ,EXP,ENG "Devos
R &: NAR, 10, 2487-2502, 1982 CLO,GEN,SEQ "Gray PW, Goeddel: Nature, 298, (26 Aug), 859-863, 1982 PEP,SEQ,EXP,ENG "Hardy &: PNAS, 82, N23, 8173-8177, 1985 PEP,SEQ,EXP,ENG "Jay &: JBC, 259, N10, 6311-6317, 1984 PEP,SEQ,EXP,ENG "Kelker &: JBC, 259, N7, 4301-4304, 1984 PEP,SEQ,EXP,ENG "Nathan &: J Exp Med, 158, 670-689, 1983 LOC,CYG,MOL "Naylor &: J Exp Med, 57, (Mar), 1020-1027, 1983 PEP,SEQ,EXP,ENG "Rinderknecht E &: JBC, 259, N11, 6790-6797, 1984 PEP,SEQ,EXP,ENG "Scahili &: PNAS, 80, (Aug), 4654-4658, 1983 PEP,SEQ,EXP,ENG "Taniguchi &: PNAS, 78, N6, 3469-3472, 1981 LOC,CYG,MOL "Trent JM &: PNAS, 79, (Dec), 7809-7813, 1982 PEP,SEQ,EXP,ENG "Yip &: PNAS, 79, 1820-1824, 1982 |
SWI | SWISSPROT: P01579 |
KEY | imm |
CLA | coding, basic |
LOC | 12 q24.1 |
MIM | MIM: 147570 |
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