Gene: [12q2/ATP2A2] ATPase, Ca++ transporting, cardiac muscle, slow twitch 2; sarcoplasmic reticulum Ca(2+)-ATPase 2;


FUN

[1] Systematic name: ATP phosphohydrolase (Ca(2+)-transporting).
[2] The reaction catalyzed: ATP + H(2)O = ADP + orthophosphate."

EXP

Sarcoplasmic reticulum type isoform (class1) and endoplasmic reticulum type (class 2) isoforms are produced by alternative splicing."

FAG

See GEM:16p121/ATP2A1 & FAM:ATP/00.0.

REF

FUN,PEP,EVO "Brandl CJ &: Cell, 44, (Feb 28), 597-607, 1986
FUN,PEP,EVO "Gunteski-Hamblin &: JBC, 263, N29, 15032-15040, 1988
PRO,SEQ,EXP "Lytton J, MacLennan: JBC, 263, N29, 15024-15031, 1988
LOC "MacLennan DH &: Somat Cell Mol Genet, 13, 341-346, 1987
FUN,PEP,EVO "MacLennan DH &: Nature, 316, (Aug 22), 696-700, 1985
FUN,PEP,EVO "Shull, Greeb: JBC, 263, N18, 8646-8657, 1988

SWI

SWISSPROT: P16614; ATCE P16615

KEY

neu, card, myo, ion

CLA

coding, basic

LOC

12 q23-24.1

MIM

MIM: 108740

EZN

ENZYME: 3.6.1.38

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