Gene: [15q1/MANAA] mannosidase, alpha A, cytoplasmic;
|
NOM |
To avoid confusion, the GEM Catalogue adopted the modified denotation for alpha-mannosidase genes: MANAA - alpha A, cytoplasmic; MANAB - alpha B, lysosomal (GEM:19q1/MANB); alpha, type II (GEM:05q2/MANA2); alpha, type II(X) (GEM:15q25/MAN2A2); and man9-alpha, type II (GEM:00.0/MAN1A1)." |
|
FAG |
On beta-mannosidase see GEM:04q2/MANBA and GEM:00.0/MANBB. |
|
FUN |
Systematic name: alpha-D-mannoside mannohydrolase. The enzyme catalyzes hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Also can hydrolyse alpha-D-lyxosides and heptopyranosides with the same configuration at C-2, C-3 and C-4 as mannose." |
|
REF |
LOC,CYG "Champion MJ &: CCG, 22, (HGM6), 498-502, 1978 LOC,CYG "Neri G &: Am J Med Genet, 14, 307-314, 1983 |
|
KEY |
carb |
|
CLA |
coding, basic |
|
LOC |
15 q11-13 |
|
MIM |
MIM: 154580 |
|
EZN |
ENZYME: 3.2.1.24 |
