Gene: [16q13/GNAO1] guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O;


GEN

The gene length: 90 kb (or more). Exons: 10 (or more).

FUN

See FAM:GNBP/00.0.

EXP

Two variant peptides, GOA and GOB, are produced as a result of alternative splicing. The amino acid sequences of these variants are identical within 700 residues from 5'-terminus. The peptides are found in various tissues, but in greatest amounts, in those of brain."

REF

SEQ "Bray P &: PNAS, 83, N22, 8893-8897, 1986
REV "Lochrie, Simon: Biochemistry, 27, N14, 4957-4965, 1988
EVO,SEQ,MAM "Meurs &: PNAS, 84, N10, 3107-3111, 1987
REV "Neer, Clapham: Nature, 333, (12 May), 129-134, 1988
EVO "Ovchinnikov YA &: FEBS Lett, 223, 169-173, 1987a
EVO "Ovchinnikov YA &: FEBS Lett, 226, 91-95, 1987b
SEQ,GEN "Strathmann &: PNAS, 87, N17, 6477-6481, 1990

SWI

SWISSPROT: P09471; GB02 P29777

KEY

neu, sign

CLA

coding, basic

LOC

16 q13

MIM

MIM: 139311