Gene: [17q25/CD7] antigen CD7 (p41; monoclonal antibodies 3A1,4A,TR41,Tp40); [p41 ]


GEN

Gene length: 3.5 kb; exons: 4 (Schanberg-1991).

MOP

The product of this gene is a membrane surface glycoprotein expressed on thymocytes and mature T lymphocytes, i.e., it is one of the T cell differentiation antigens; these are used as markers of T-cell acute lymphocytic leukemias."

REL

GEM:11q2/THY1.

REF

LOC,PRO "Adriaansen AJ &: CCG, 46, (HGM9), N1-4, 567-568, 1987
PRO,SEQ,COD,EXP "Aruffo A, Seed B: EMBO J, 6, 3313-3316, 1987
LOC,MOL,CYG "Baker E &: Immunogenetics, 31, 412-413, 1990
LOC,PRO "Osada S &: CCG, 47, 8-10, 1988
PRO,GEN,SEQ "Schanberg LE &: PNAS, 88, 603-607, 1991
LOC,PRO "Van Dongen JJM &: J Immunol, 137, 1047-1053, 1986
LOC,PRO "Van Dongen JJM &: CCG, 40, (HGM8), N1-4, 767, 1985
PRO,GEN,SEQ "Yoshikawa K &: Immunogenetics, 33, 352-360, 1991

KEY

imm, mem

CLA

coding, basic

LOC

17 q25.2-.3

MIM

MIM: 186820

SYN

p41