Gene: [17q2/TOP2A] topoisomerase (DNA) II alpha (170kD);
|
EVO |
The enzyme is analagous to bacterial DNA gyrase. |
|
FAG |
Gene for DNA topoisomerase I is mapped to the long arm of Chr 20: GEM:20q1/TOP1. Gene for DNA beta topoisomerase II is mapped to Chr 3: GEM:03p24/TOP2B." |
|
REF |
REV,FUN,MOP "Austin CA, Fisher LM: Science Progress, 74, N294 (Part 2),
147-162, 1990 MUT "Campain J &: Biochemistry, 33, N37, 11327-11332, 1994 CLO,SEQ,GEN "Loflin PT &: BBRC, 200, N1, 489-496, 1994 LOC "Tan KB &: Cancer Res, 52, N1, 231-234, 1992 PRO,SEQ,LOC "Tsai-Pflugfelder M &: PNAS, 85, N19, 7177-7181, 1988 |
|
KEY |
repr, chr |
|
CLA |
coding, basic |
|
LOC |
17 q21-22 |
|
MIM |
MIM: 126430 |
|
EZN |
ENZYME: 5.99.1.3 |
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