Gene: [19p131/MEL] cell line NK14 derived transforming oncogene; oncogene RAS-family, member rab8 homolog; [RAB8 ]


COM

Although MEL gene was first identified in melanoma cells, its relationship with the development of this tumor is not determined."

LIN

Loci: GEM:19p132/LDLR; GEM:19p131/MYO9B.
[1] MEL is tightly linked with D19S11.
[2] MEL is linked with LDLR.
[3] MEL is linked with MYO9B (Bahler-1997)."

PRO

Gene-specific DNA probe pC7-1 is a 2.0 kb fragment cloned at EcoRI site in the vector pEMBL8 (Padua-1984)."

POL

[1] NcoI A1= 4.0/(0.73); A2= 3.8/(0.27); (Nimmo-1987; Probe 1);
[2] NotI (Nimmo-1989)."

LIK

GEM:19p131/MELL1.

REF

LOC,LIN,MAF "Bahler M &: Genomics, 43, 107-109, 1997
LOC "Brandriff BF &: Genomics, 23, 582-591, 1994
LOC,LIN,POL,PAT "Nimmo ER &: CCG, 58, 2022, 1991
LOC,LIN,POL,PAT "Nimmo ER &: Hum Genet, 81, N4, 382-384, 1989
PRO,POL "Nimmo ER &: NAR, 15, 3940, 1987
IDN,PRO,MEB "Padua RA &: Nature, 311, 671-673, 1984
LOC "Spurr NK &: Somat Cell Mol Genet, 12, 637-640, 1986

KEY

onc

CLA

coding, basic

LOC

19 p13.1

MIM

MIM: 165040

SYN

RAB8