Gene: [22q112/MIF] macrophage migration inhibitory factor; glycosylation-inhibiting factor; phenylpyruvate tautomerase;


FUN

A macrophage migration inhibitory factor, originally described as a product of activated lymphocytes, was identified as a phenylpyruvate tautomerase (Resengren-1997, Suzuki-1997). It has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation."

REF

CLO,SEQ,STR "Bernhagen J &: Biochemistry, 33, N47, 14144-14155, 1994
CLO,SEQ,STR,HET,LOC,MOU "Bozza M &: Genomics, 27, N3, 412-419, 1995
FUN "Bucala R: FASEB J, 10, N14, 1607-1613, 1996
LOC "Budarf M &: Genomics, 39, N2, 235-236, 1997
LOC "Kozak CA &: Genomics, 27, N3, 405-411, 1995
CLO,SEQ "Mikayama T &: PNAS, 90, 10056-10060, 1993
CLO,SEQ "Paralkar V, Wistow GJ: Genomics, 19, 48-51, 1994
FUN "Rosengren E &: FEBS Lett, 417, N1, 85-88, 1997
FUN "Suzuki M &: J Biochem, 122, N5, 1040-1045, 1997
CLO,SEQ "Weiser WY &: PNAS, 86, 7522-7526, 1989
CLO,SEQ,EXP "Wistow GJ &: PNAS, 90, N4, 1272-1275, 1993

KEY

cyk

CLA

coding, basic

LOC

22 q11.2

MIM

MIM: 153620

EZN

ENZYME: 5.3.2.1

鸯铗痂蝈 蜞赕:

  • 髓祠铌桧, 溴轳蜮簋 磬 爨牮铘嚆
  • Gene: [00.0/DDT] D-dopachrome tautomerase (phenylpyruvate tautomerase II);