Gene family: cadherins and catenins (cadherin-associated proteins); (CDH1 CDH2 CDH3 CDH4 CDH5 CDH6 CDH7 CDH8 CDH9 CDH10 CDH11 CDH12 CDH12P CDH13 CDH15 CDH16 CDH17 CDH18 CDH19 CDH20 CDH21 @CTNN PCDH1 PCDH2 PCDH3 PCDH7 PCDH8 PCDH9)

SUM

Members of the cadherin superfamily of proteins are membrane-associated glycoproteins that mediate calcium-dependent cell-cell adhesion. All have an extracellular domain containing repeats of the approximately 110-amino acid cadherin motif, a transmembrane domain, and a relatively small cytoplasmic domain. Protocadherins (Pcdhs), which comprise one class of cadherins, seem to function as cell-cell recognition molecules and as components in a signal transduction pathway."